VasoDrive-AP™ is a newer ingredient to hit the market and is a very unique one. It’s a vasodilator, but it works differently from any other pump ingredient out. VasoDrive-AP™ consists of 2 lactotripeptides: Valyl-prolyl-proline and Isoluecyl-prolyl-proline. These 2 molecules act as inhibitors of the enzyme angiotensin converting enzyme(ACE), an enzyme that causes vasoconstriction, increased blood pressure and heart function. There are 30 studies on these lactotripeptides and their effect on vasodilation, blood flow, and decreased blood pressure. One study showed that ACE can dramatically inhibit physical performance, presumably from lack of blood flow which carries oxygen and nutrients to your muscles. Data also suggests that VasoDrive-AP™ works better the longer you take it.
This ingredient adds a completely different mechanism for increased blood flow and is used at the clinical of 254mg. S7™: S7(SPECTRA7)™ is a new ingredient that was just released late last year. It, like VasoDrive-AP™ has a completely new and different mechanism of action for increasing vasodilation. S7™ is made up of a proprietary blend of 7 plant-based ingredients that work in increase endogenous NO production by 230% according to one study. S7™ works by inhibiting mitochondrial and cellular reactive oxygen species(ROS) generation via antioxidants by up to 17%. Free radicals and ROS can damage cells and your mitochondria, which is where your body produces ATP(energy). The study also showed a reduction of the O2 radical and the generation of hydrogen peroxide(another free radical generator) by 14.8% and 44.5%, respectively. By inhibiting ROS and inflammatory enzymes like TNF, the bioavailability of NO was increased by 230%. This happens bc NO is also a radical and can bind to ROS and free radicals(due to unpaired electrons), rendering it useless for vasodilation. NO production was shown in a dosedependent manner, with as little as 50mg being effective. We used 100mg of S7™ in this formula.