Catuaba (Trichilium catigua) has been used in traditional Brazilian medicine for its antidepressant and memory-stimulant properties(as well as libido). Catuaba Bark works mostly on modulating dopamine, which users report improved mood, enhanced cognition and focus, as expected. Remember, dopamine is released and reuptake is blocked in medications for ADHD, so this makes sense. According to the research, Catuaba not only boosts dopamine release and inhibits its transport/reuptake, it also increases sensitivity of your D1 dopamine receptor. It’s also been shown to increase acetylcholine via acting as a mild acetylcholinesterase(enzyme that breaks down acetylcholine) inhibitor. Some research even suggests that it can increase the release and inhibit the reuptake of serotonin, as well. However, its mostly dopaminergic which is why it’s in this formula. It also has neuroprotective properties against oxidative stress. This compound is a superstar ingredient that not only will give you plenty of energy and dopamine, but focus, as well.