Here is what happens: Below is an abstract from a clinical study performed to clarify the negative effects of increased ammonia in the blood.
In this article we propose that exercise-induced hyperammonemia may lead to concomitant disturbances in brain function, potentially through similar mechanisms underpinning pathology, which may impact on performance as fatigue or reduced function, especially during extreme exercise.
Summary: Everyone who trains hard may exceed their bodies ability to produce enough ATP to get through the toughest workouts. And high intensity exercise causes increased circulating ammonia which can lead to impaired brain function, clarity and focus.
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